A Time-Domain Electromagnetic Transmitter with Great Power and Large Current by Using a Closed-Loop Phase Shifting Control Strategy

A time-domain electromagnetic transmitter (TDET) with great power and large current was designed by using a closed-loop phase shifting control strategy. A clamping voltage source circuit was applied in this system to improve the falling edge of emission current and shorten the turn-off time. The simulated results showed that this TDET exhibited the advantages including a large current, strong capability for rapid turn-off, stably output voltage, preferably dynamic performance, a widely adjustable range in transmitting voltage, accurate measurement precision.     

Software Module Clustering Algorithm Using Probability Selection

Software module clustering problem is an important and challenging problem in software reverse engineering whose main goal is to obtain a good modular structure of the software system. The large complex software system can be divided into some subsystems that are easy to understand and maintain through the software module clustering. Aiming at solving the problem of slow convergence speed, the poor clustering result, and the complex algorithm, a software module clustering algorithm using probability selection is proposed. Firstly, we convert the software system into complex network diagram, and then we use the operation of merger, adjustment and optimization to get the software module clustering scheme. To evaluate the effectiveness of the algorithm, a set of experiments was performed on 5 real-world module clustering problems. The comparison of the experimental results proves the simplicity of the algorithm as well as the low time complexity and fast convergence speed. This algorithm provides a simple and effective engineering method for software module clustering problem.     

Fingerprint Core Location Algorithm Based on Sliding Window

In order to improve the efficiency of the fingerprint core location algorithm, a fingerprint core location method using sliding window on the basis of core location algorithm with the complex filter was proposed. The local region of the fingerprint image was extracted by a fixed-size window sliding in the region of the fingerprint image, and the selected local region by window as the calculation object is used to detect the core. The experiment results show that the method cannot only effectively detect fingerprint core, but also improve the efficiency of the detection algorithm comparing with the global fingerprint core location detection algorithm.     

Generation of Linear and Parabolic Concentration Gradients by Using a Christmas Tree-Shaped Microfluidic Network

This paper describes a simple method of generating concentration gradients with linear and parabolic profiles by using a Christmas tree-shaped microfluidic network.The microfluidic gradient generator consists of two parts:a Christmas tree-shaped network for gradient generation and a broad microchannel for detection.A two-dimensional model was built to analyze the flow field and the mass transfer in the microfluidic network.The simulating results show that a series of linear and parabolic gradient profiles were generated via adjusting relative flow rate ratios of the two source solutions(R_L~2≥0.995 and _PR~2≥0.999),which could match well with the experimental results(R_L~2≥0.987 and _PR~2≥0.996).The proposed method is promising for the generation of linear and parabolic concentration gradient profiles,with the potential in chemical and biological applications such as combinatorial chemistry synthesis,stem cell differentiation or cytotoxicity assays.     

空气污染对儿童大脑发育的影响

目的综述空气污染对儿童身体健康的影响,特别是对于儿童大脑发育的影响,为控制污染和保护儿童健康成长提供参考依据。方法利用文献法对国内外40余篇关于空气污染对儿童大脑发育影响的参考文献进行概述。结果 (1)生活在世界各地大中城市的一些儿童群体样本出现的一定程度神经、行为和认知变化与空气污染暴露有关;(2)怀孕动物产前暴露于单一或复合标准污染物,其子代会产生神经递质永久性变化,同时改变大脑发育;(3)天然屏障(如血脑屏障、鼻腔、肠和肺上皮屏障)的健康发展对儿童健康发育结果至关重要:(4)空气污染会导致大脑中广泛性神经炎症,进而造成大脑各个部位神经组织的损伤和弥漫性损失,最终影响认知功能的发展。(5)接触空气污染物可能会对脊髓的髓鞘和中枢神经系统中神经元的功能产生有害影响,也会使促炎症介质中神经炎症与细胞损失明显增加。结论面对严重的空气污染,对青少年健康特别是对儿童大脑发育的影响日益受到人们的关注。未来研究不仅需要严格控制污染物排放标准,保护人类生存环境;而且需要采用多种技术,进行跨学科协作研究,以实现对暴露于空气污染物环境条件下的儿童进行有效保护,同时也需要制定有效策略,从健康教育和流行病学角度进行深入研究,监测空气污染物对儿童健康的影响,确保儿童健康成长。     

Critical Chords of Convex Bodies of Constant Width

In this paper, we show that when Minkowski measure of asymmetry of convex body K of constant width is bigger than α (n-1), K has at least n+1 critical chords, where \(\alpha (n) = \frac{{n + \sqrt {2n(n + 1)} }}{{n + 2}}\).     

Wiener Indices in Random Cyclooctane Chains

The Wiener index of a connected graph (molecule graph) G is the sum of the distances between all pairs of vertices of G. In this paper, simple exact formula are established for the expected value of Wiener index in random cyclooctane chain. Moreover, we obtain the average value of the Wiener indices with respect to the set of all cyclooctane chains with n octagons.     

姜黄素长循环脂质体的制备及表征

为了改善姜黄素长循环脂质体(Cur-LCL)的稳定性,延长药物在体内的循环时间,对现有姜黄素脂质体(Cur-Lips)和姜黄素长循环脂质体的制备方法进行了优化。使用乙醇注入法制备Cur-Lips,用后插法将DSPE-PEG2000插入Cur-Lips中制成Cur-LCL。结果表明:Cur-LCL外观为圆形囊泡状球体,平均包封率为(88.91±0.94)%,4℃存放15d包封率没有明显变化,平均渗漏率为2.4%,具有较好的稳定性;Cur-LCL平均粒径为(118.4±3.2)nm(n=3),呈单峰分布,平均电位为(-12.9±0.32)mV(n=3);以溶解度为标准对溶出介质进行筛选,选择以1%Tween 80的生理盐水为体外释放试验的溶出介质,Cur原料药12h基本释放完全,Cur-Lips在36h基本释放完全,累计释放率为92.67%,Cur-LCL在72h基本释放完全,累计释放率为91.36%。Cur-LCL具有明显的缓释性,可以延长药物在血液中的循环时间,达到长循环的效果。     

腔内血管成形术治疗老年人下肢动脉硬化闭塞症临床疗效及安全性评价

目的探讨腔内血管成形术(PTA)治疗老年人下肢动脉硬化闭塞症(ASO)的临床疗效及安全性评价.方法回顾性分析160例老年下肢动脉硬化闭塞症患者的临床资料,随机分为介入组(80例,行腔内血管成形术)和对照组(80例,行下肢动脉旁路移植术),综合比较两组患者相关指标.结果介入组与对照组间ABI指数、患肢皮温、足背动脉血流动力学指标(足背动脉内径、血流峰速、血流量)、疼痛积分、下肢神经传导速度(运动神经传导速度、感觉神经传导速度)和手术成功率、术后保肢率、通畅率等比较,差异均无统计学意义(P0.05).介入组术后并发症发生率与对照组比较明显减少(P0.05).结论腔内血管成形术治疗老年下肢动脉硬化闭塞症安全可行,临床疗效较好.     

学龄前和学龄期儿童希氏束以上心动过速性心肌病高危因素分析

目的探讨学龄前和学龄期儿童希氏束以上的心动过速(室上性心动过速)与心动过速性心肌病的相关性及高危因素.方法选取室上性心动过速患儿179例,根据心动过速时心功能状态分为心肌病组23例,非心肌病组156例.分析患儿性别、年龄、发作类型、发作频率、持续时间、心室率与心功能损伤的关系和相关高危因素.结果 179例患儿中心动过速性心肌病23例,其中房室折返性、房室结折返性、无明确分类的心肌病分别为7例、10例、6例.房速所致心动过速性心肌病发生率为25.00%(8/32),明显高于阵发性室上性心动过速所致的心肌病发生率10.20%(15/147),差异具有统计学意义(P0.05).心肌病组患儿中房速所占比例、发作持续时间明显高于非心肌病组患儿,发作频率明显低于非心肌病组患儿,差异均具有统计学意义(P0.05).二元Logistic回归分析显示:发作持续时间是心动过速性心肌病的独立影响因素.结论学龄前和学龄期儿童室上性心动过速所致心动过速性心肌病的发生率为12.85%,其中房速所致的心肌病发生率明显高于阵发性室上性心动过速,发作持续时间是唯一高危因素.